Flowers, produced by Momordica cochinchinensis appear solitary or in a bundle in males. The flowers are fuzzy and typically 5–10 cm (2.0–3.9 in) in length.

The fruit itself becomes a dark orange color upon ripening, and is typically round or oblong, maturing to a size of about 13 cm (5.1 in) in length and 10 cm (3.9 in) in diameter. Its exocarp, or exterior skin, is covered in small spines. Its mesocarp is dense, light-orange in color, and has a mild taste with flavor similar to that of cucumber. The edible seeds are brown or black in color, surrounded by dark red membraneous sacs, and have a mild, nutty flavor